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phosphorylated eif-2α  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc phosphorylated eif-2α
    Phosphorylated Eif 2α, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/phosphorylated eif-2α/product/Cell Signaling Technology Inc
    Average 90 stars, based on 1 article reviews
    phosphorylated eif-2α - by Bioz Stars, 2026-03
    90/100 stars

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    Image Search Results


    Poricoic acid A (PAA) inhibited endoplasmic reticulum stress (ERS) activation in the kidney of unilateral ureteral obstruction (UUO) mice. A and B , Protein expression and quantitative analysis of Chop, GRP78, p-PERK, p-eif-2α, and ATF4. C , mRNA expression of Chop, GRP78, and ATF4. D , Immunohistochemical staining of Chop and GRP78 and relative quantitative analysis. Scale bar 25 μm. Data are reported as means±SD. *P<0.05, **P<0.01, ***P<0.001, and ns: not statistically significant. One-way ANOVA followed by a two-tailed Student's t -test. LOS: losartan.

    Journal: Brazilian Journal of Medical and Biological Research

    Article Title: Poricoic acid A attenuates renal fibrosis by inhibiting endoplasmic reticulum stress-mediated apoptosis

    doi: 10.1590/1414-431X2024e14249

    Figure Lengend Snippet: Poricoic acid A (PAA) inhibited endoplasmic reticulum stress (ERS) activation in the kidney of unilateral ureteral obstruction (UUO) mice. A and B , Protein expression and quantitative analysis of Chop, GRP78, p-PERK, p-eif-2α, and ATF4. C , mRNA expression of Chop, GRP78, and ATF4. D , Immunohistochemical staining of Chop and GRP78 and relative quantitative analysis. Scale bar 25 μm. Data are reported as means±SD. *P<0.05, **P<0.01, ***P<0.001, and ns: not statistically significant. One-way ANOVA followed by a two-tailed Student's t -test. LOS: losartan.

    Article Snippet: The primary antibodies included: collagen I (1:5000, ab34710, Abcam), fibronectin (1:1000, ab2413, Abcam), vimentin (1:2000, ab92547, Abcam), α smooth muscle actin (α-SMA,1:300, ab7817, Abcam), E-cadherin (1:2000, ab76055, Abcam), CHOP (1:1000, 2895, CST), GRP78 (1:1000, ab108615, Abcam), eIF-2α (1:1000, 9722, CST), P-eIF-2α (1:1000, 9721, CST), ATF4 (1:1000, AF2560, Beyotime), and α-tubulin (Proteintech).

    Techniques: Activation Assay, Expressing, Immunohistochemical staining, Staining, Two Tailed Test